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Immunotherapy-based combination strategies for treatment of gastrointestinal cancers: current status

Chenfei Zhou, Jun Zhang

Frontiers of Medicine 2019, Volume 13, Issue 1,   Pages 12-23 doi: 10.1007/s11684-019-0685-9

Abstract: However, treatment options remain limited for late-stage or refractory diseases.The efficacy of immune checkpoint inhibitors (ICIs) for treatment of refractory GI cancer has been confirmedIn 2017, pembrolizumab was approved by the US Food and Drug Administration as the first agent for treatmentGiven the different mechanisms, oncologists have focused on determining whether ICIs-based combinationstrategies could achieve higher efficacy than conventional therapy alone in late-stage or even front-line treatment

Keywords： gastrointestinal cancer     immune checkpoint inhibitor     combination therapy    

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Adsorption in combination with ozonation for the treatment of textile waste water: a critical review

Shraddha Khamparia,Dipika Kaur Jaspal

Frontiers of Environmental Science & Engineering 2017, Volume 11, Issue 1, doi: 10.1007/s11783-017-0899-5

Abstract: A combination of adsorption with ozonation proved best for dye removal.Wide scope for choice of natural materials for treatment of textile dyes.diverse and complex set of physico-chemical, biological and advanced oxidation processes adopted for treatmentAdsorption in itself is a well-known technique utilized for treatment of textile effluents using a varietyThe review summarizes dye removal study by a combination of ozonation and adsorption methods.

Keywords： Adsorption     Ozonation     Catalytic Ozonation     Textile dyes     Mineralization    

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New method for efficient control of hydrogen sulfide and methane in gravity sewers: Combination of NaOH

Frontiers of Environmental Science & Engineering 2022, Volume 16, Issue 6, doi: 10.1007/s11783-021-1509-0

Abstract:

• The combination of NaOH and nitrite was used to control harmful gas

Keywords： Sewer corrosion     Sulfide control     Combination treatment     NaOH     Nitrite    

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Pesticide wastewater treatment using the combination of the microbial electrolysis desalination and chemical-production

Songwei Lin, Yaobin Lu, Bo Ye, Cuiping Zeng, Guangli Liu, Jieling Li, Haiping Luo, Renduo Zhang

Frontiers of Environmental Science & Engineering 2020, Volume 14, Issue 1, doi: 10.1007/s11783-019-1191-7

Abstract: The combination of the microbial electrolysis desalination and chemical-production cell (MEDCC) and Fentonprocess for the pesticide wastewater treatment was investigate in this study.

Keywords： Pesticide wastewater     COD removal     Microbial electrolysis desalination and chemical-production cell     Energy consumption     Fenton oxidation    

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Treatment of severe diffuse cavernous hemangioma of the lower limb by combination of superficial femoral

Yin XIA, Dan SHANG, Qin LI, Xiaoqin RUN, Chenxi OUYANG, Yiqing LI, Bi JIN

Frontiers of Medicine 2009, Volume 3, Issue 2,   Pages 240-244 doi: 10.1007/s11684-009-0031-8

Abstract: Severe diffuse cavernous hemangioma of the lower limb is rarely seen among young people and sometimes can be a fatal challenge for operation. We reported a case of diffuse cavernous hemangioma involving both skin and muscles of the left lower limb and perineal region in an adolescent patient. The patient who had previously undergone a local hemangioma resection of the foot ultimately ended in superficial femoral artery ligation and supergenual thigh amputation of the left upper leg because of uncontrollable massive bleeding of anastomotic stoma.

Keywords： cavernous hemangioma     femoral artery     ligation     amputation    

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Performance of a hybrid anaerobic-contact oxidation biofilm baffled reactor for the treatment of decentralized

Minmin LIU,Ying ZHAO,Beidou XI,Li’an HOU,Xunfeng XIA

Frontiers of Environmental Science & Engineering 2014, Volume 8, Issue 4,   Pages 598-606 doi: 10.1007/s11783-013-0576-2

Abstract: based on the inoculation of anaerobic granule sludge in anaerobic compartments and the installation of combination

Keywords： combination filler     contact oxidation biofilm     food wastewater     anaerobic baffled reactor    

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Combination of the direct electro-Fenton process and bioremediation for the treatment of pyrene-contaminated

Wendi XU,Shuhai GUO,Gang LI,Fengmei LI,Bo WU,Xinhong GAN

Frontiers of Environmental Science & Engineering 2015, Volume 9, Issue 6,   Pages 1096-1107 doi: 10.1007/s11783-015-0804-z

Abstract: A combined treatment technology (DEF-BIO) using the direct electro-Fenton (DEF) process and bioremediation

Keywords： direct electro-Fenton     bioremediation     slurry reactor     combined process     pyrene    

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Removal of virus aerosols by the combination of filtration and UV-C irradiation

Frontiers of Environmental Science & Engineering 2023, Volume 17, Issue 3, doi: 10.1007/s11783-023-1627-y

Abstract:

● The removal of virus aerosols by filtration and UV-C irradiation was proposed.

Keywords： Filtration system     UV-C irradiation     Virus aerosol     Public health     COVID-19    

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Studies on Combination Evaluation Methods Based on Nature Differenc

Chen Yantai,Chen Guohong,Li Meijuan

Strategic Study of CAE 2005, Volume 7, Issue 8,   Pages 56-59

Abstract: Secondly, it puts forward one new combination evaluation method , in order to solve the problem of inconsistencies

Keywords： evaluation methods with different nature     combination evaluation     re-combination    

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Silica-based nanoarchitecture for an optimal combination of photothermal and chemodynamic therapy functions

Frontiers of Chemical Science and Engineering 2023, Volume 17, Issue 12,   Pages 2144-2155 doi: 10.1007/s11705-023-2362-4

Abstract: This study introduces multifunctional silica nanoparticles that exhibit both high photothermal and chemodynamic therapeutic activities, in addition to luminescence. The activity of the silica nanoparticles is derived from their plasmonic properties, which are a result of infusing the silica nanoparticles with multiple Cu2–xS cores. This infusion process is facilitated by a recoating of the silica nanoparticles with a cationic surfactant. The key factors that enable the internal incorporation of the Cu2–xS cores and the external deposition of red-emitting carbon dots are identified. The Cu2–xS cores within the silica nanoparticles exhibit both self-boosting generation of reactive oxygen species and high photothermal conversion efficacy, which are essential for photothermal and chemodynamic activities. The silica nanoparticles’ small size (no more than 70 nm) and high colloidal stability are prerequisites for their cell internalization. The internalization of the red-emitting silica nanoparticles within cells is visualized using fluorescence microscopy techniques. The chemodynamic activity of the silica nanoparticles is associated with their dark cytotoxicity, and the mechanisms of cell death are evaluated using an apoptotic assay. The photothermal activity of the silica nanoparticles is demonstrated by significant cell death under near-infrared (1064 nm) irradiation.

Keywords： copper sulfide nanoparticles     chemodynamic therapy     photothermal therapy     carbon dots     silica nanoparticles    

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approach of low carbon and efficient utilization of coal resources: The polygeneration system of a combination

Kechang XIE, Fan LI

Frontiers of Chemical Science and Engineering 2010, Volume 4, Issue 4,   Pages 383-384 doi: 10.1007/s11705-010-0526-5

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Celecoxib in combination with retinoid CD437 inhibits melanoma A375 cell

Jianwen REN, Zhenhui PENG, Birong GUO, Min PAN

Frontiers of Medicine 2009, Volume 3, Issue 1,   Pages 108-112 doi: 10.1007/s11684-009-0015-8

Abstract: synthetic retinoid 6-[3-(1-adamantyl)-4-hydroxyphenyl]-2-naphthalenecarboxylic acid (CD437) and the combinationproliferation, induced apoptosis and G /M cell cycle arrest of human malignant melanoma A375 cells after treatmentCelecoxib in combination with CD437 could significantly enhance the effects of inhibiting proliferationand inducing apoptosis of human malignant melanoma A375 cells 24 h after treatment compared with theCelecoxib in combination with CD437 may become an effective method for prevention and treatment of human

Keywords： celecoxib     CD437     melanoma A375 cell     apoptosis     cycle arrest    

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Combination form analysis and experimental study of mechanical properties on steel sheet glass fiber

Frontiers of Structural and Civil Engineering 2021, Volume 15, Issue 4,   Pages 834-850 doi: 10.1007/s11709-021-0743-7

Abstract: Three-dimensional finite element analysis was adopted to perform the combination form optimization of

Keywords： steel sheet GFRP composite bar     combination form     numerical modeling     mechanical properties test     strength    

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Bevacizumab in combination with pemetrexed and platinum for elderly patients with advanced non-squamous

Frontiers of Medicine 2022, Volume 16, Issue 4,   Pages 610-617 doi: 10.1007/s11684-021-0827-8

Abstract: Bevacizumab, an anti-VEGF monoclonal antibody, has significantly improved the clinical outcomes of patients with advanced non-squamous NSCLC (ns-NSCLC). However, the safety and efficacy of bevacizumab for elderly patients with advanced NSCLC require further investigation. Thus, 59 patients were included in the present retrospective study, 22 patients in the bevacizumab plus pemetrexed and platinum (B+PP) group, and 37 patients in the pemetrexed and platinum (PP) group. For the entire cohort of patients, the median OS was 33.3 months, and the 1-year and 2-year overall survival rates were 88.5% and 67.8%, respectively. The median OS and 1-year and 2-year OS rates were 20.5 months, 70.3% and 0%, respectively, in the B+PP group and 33.4 months, 97.0% and 89.4%, respectively, in the PP group (P <0.001). The incidence of grade≥3 adverse events was higher in the B+PP group than in the PP group (27.3% vs. 10.8%, respectively; P=0.204). Univariate and multivariate analyses suggested that the receipt of≥5 cycles of first-line chemotherapy was an independent favorable prognostic factor for OS, whereas the addition of bevacizumab was an unfavorable prognostic factor. With increased toxicities, the addition of bevacizumab to PP does not improve the overall survival of elderly patients with advanced ns-NSCLC.

Keywords： bevacizumab     elderly patient     advanced non-small-cell lung cancer     overall survival     toxicity    

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The value of radionuclide hepatobiliary scintigraphy in combination with determination of bilirubin from

Sheng-Xuan LIU, Zhi-Hua HUANG

Frontiers of Medicine 2010, Volume 4, Issue 3,   Pages 342-345 doi: 10.1007/s11684-010-0099-1

Abstract: to investigate the value of technetium etifenin injection ( Tc-EHIDA) hepatobiliary scintigraphy in combinationTc-EHIDA hepatobiliary scintigraphy in combination with duodenal fluid examination was used for evaluationscintigraphy were 100% and 74.5%, respectively; the sensitivity and specificity of scintigraphy in combinationconclusion, hepatobiliary scintigraphy, which is a noninvasive, safe, valuable examination method, in combination

Keywords： jaundice     radionuclide hepatobiliary scintigraphy     duodenal drainage    

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Title Author Date Type Operation

Immunotherapy-based combination strategies for treatment of gastrointestinal cancers: current status

Chenfei Zhou, Jun Zhang

Journal Article

Adsorption in combination with ozonation for the treatment of textile waste water: a critical review

Shraddha Khamparia,Dipika Kaur Jaspal

Journal Article

New method for efficient control of hydrogen sulfide and methane in gravity sewers: Combination of NaOH

Journal Article

Pesticide wastewater treatment using the combination of the microbial electrolysis desalination and chemical-production

Songwei Lin, Yaobin Lu, Bo Ye, Cuiping Zeng, Guangli Liu, Jieling Li, Haiping Luo, Renduo Zhang

Journal Article

Treatment of severe diffuse cavernous hemangioma of the lower limb by combination of superficial femoral

Yin XIA, Dan SHANG, Qin LI, Xiaoqin RUN, Chenxi OUYANG, Yiqing LI, Bi JIN

Journal Article

Performance of a hybrid anaerobic-contact oxidation biofilm baffled reactor for the treatment of decentralized

Minmin LIU,Ying ZHAO,Beidou XI,Li’an HOU,Xunfeng XIA

Journal Article

Combination of the direct electro-Fenton process and bioremediation for the treatment of pyrene-contaminated

Wendi XU,Shuhai GUO,Gang LI,Fengmei LI,Bo WU,Xinhong GAN

Journal Article

Removal of virus aerosols by the combination of filtration and UV-C irradiation

Journal Article

Studies on Combination Evaluation Methods Based on Nature Differenc

Chen Yantai,Chen Guohong,Li Meijuan

Journal Article

Silica-based nanoarchitecture for an optimal combination of photothermal and chemodynamic therapy functions

Journal Article

approach of low carbon and efficient utilization of coal resources: The polygeneration system of a combination

Kechang XIE, Fan LI

Journal Article

Celecoxib in combination with retinoid CD437 inhibits melanoma A375 cell

Jianwen REN, Zhenhui PENG, Birong GUO, Min PAN

Journal Article

Combination form analysis and experimental study of mechanical properties on steel sheet glass fiber

Journal Article

Bevacizumab in combination with pemetrexed and platinum for elderly patients with advanced non-squamous

Journal Article

The value of radionuclide hepatobiliary scintigraphy in combination with determination of bilirubin from

Sheng-Xuan LIU, Zhi-Hua HUANG

Journal Article